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Sex-Specific Metabolic Effects of Dietary Folate Withdrawal in Wild-Type and Aldh1l1 Knockout Mice

ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism, is highly expressed in the liver. It regulates the overall flux of folate-bound one-carbon groups by converting 10-formyltetrahydrofolate to tetrahydrofolate and CO(2) in a NADP(+)-dependent reaction. Our previous stu...

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Detalles Bibliográficos
Autores principales:	Sharma, Jaspreet, Rushing, Blake R., Hall, Madeline S., Helke, Kristi L., McRitchie, Susan L., Krupenko, Natalia I., Sumner, Susan J., Krupenko, Sergey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143804/ https://www.ncbi.nlm.nih.gov/pubmed/35629957 http://dx.doi.org/10.3390/metabo12050454

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