Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole

Antimicrobial drug resistance is currently one of the most critical health issues. Pathogens resistant to last-resort antibiotics are increasing, and very few effective antibacterial agents have been introduced in recent years. The promising drug candidates are often discontinued in the primary stag...

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Detalles Bibliográficos
Autores principales: Juhás, Martin, Bachtíková, Andrea, Nawrot, Daria Elżbieta, Hatoková, Paulína, Pallabothula, Vinod Sukanth Kumar, Diepoltová, Adéla, Janďourek, Ondřej, Bárta, Pavel, Konečná, Klára, Paterová, Pavla, Šesták, Vít, Zitko, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143880/
https://www.ncbi.nlm.nih.gov/pubmed/35631406
http://dx.doi.org/10.3390/ph15050580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143880/
https://www.ncbi.nlm.nih.gov/pubmed/35631406
http://dx.doi.org/10.3390/ph15050580

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