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Exploring Natural Product Activity and Species Source Candidates for Hunting ABCB1 Transporter Inhibitors: An In Silico Drug Discovery Study

The P-glycoprotein (P-gp/ABCB1) is responsible for a xenobiotic efflux pump that shackles intracellular drug accumulation. Additionally, it is included in the dud of considerable antiviral and anticancer chemotherapies because of the multidrug resistance (MDR) phenomenon. In the search for prospecti...

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Detalles Bibliográficos
Autores principales:	Ibrahim, Mahmoud A. A., Abdeljawaad, Khlood A. A., Abdelrahman, Alaa H. M., Jaragh-Alhadad, Laila A., Oraby, Hesham Farouk, Elkaeed, Eslam B., Mekhemer, Gamal A. H., Gabr, Gamal A., Shawky, Ahmed M., Sidhom, Peter A., Soliman, Mahmoud E. S., Moustafa, Mahmoud F., Paré, Paul W., Hegazy, Mohamed-Elamir F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143904/ https://www.ncbi.nlm.nih.gov/pubmed/35630581 http://dx.doi.org/10.3390/molecules27103104

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