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Extracellular Vesicles from M1-Polarized Macrophages Combined with Hyaluronic Acid and a β-Blocker Potentiate Doxorubicin’s Antitumor Activity by Downregulating Tumor-Associated Macrophages in Breast Cancer

One of the main reasons for cancer’s low clinical response to chemotherapeutics is the highly immunosuppressive tumor microenvironment (TME). Tumor-ass ociated M2 macrophages (M2-TAMs) orchestrate the immunosuppression, which favors tumor progression. Extracellular vesicles (EVs) have shown great po...

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Detalles Bibliográficos
Autores principales:	Jorquera-Cordero, Carla, Lara, Pablo, Cruz, Luis J., Schomann, Timo, van Hofslot, Anna, de Carvalho, Thaís Gomes, Guedes, Paulo Marcos Da Matta, Creemers, Laura, Koning, Roman I., Chan, Alan B., de Araujo Junior, Raimundo Fernandes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143936/ https://www.ncbi.nlm.nih.gov/pubmed/35631654 http://dx.doi.org/10.3390/pharmaceutics14051068

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