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TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling

Osteosarcoma (OS) is a malignant bone tumor that mainly occurs in adolescents. It is accompanied by a high rate of lung metastasis, and high mortality. Recent studies have suggested the important roles of tripartite motif-containing (TRIM) family proteins in regulating various substrates and signali...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Zhao, Yuechao, Wang, Guangfu, Feng, Shuang, Ge, Xuhui, Ye, Wu, Wang, Zhuanghui, Zhu, Yufeng, Cai, Weihua, Bai, Jianling, Zhou, Xuhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144049/ https://www.ncbi.nlm.nih.gov/pubmed/35636015 http://dx.doi.org/10.1016/j.redox.2022.102344

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