Ultrarare Loss-of-Function Mutations in the Genes Encoding the Ionotropic Glutamate Receptors of Kainate Subtypes Associated with Schizophrenia Disrupt the Interaction with PSD95

Schizophrenia is a complex mental disorder with a genetic component. The GRIK gene family encodes ionotropic glutamate receptors of the kainate subtype, which are considered candidate genes for schizophrenia. We screened for rare and pathogenic mutations in the protein-coding sequences of the GRIK g...

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Detalles Bibliográficos
Autores principales: Hu, Tsung-Ming, Wu, Chia-Liang, Hsu, Shih-Hsin, Tsai, Hsin-Yao, Cheng, Fu-Yu, Cheng, Min-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144110/
https://www.ncbi.nlm.nih.gov/pubmed/35629206
http://dx.doi.org/10.3390/jpm12050783

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