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Infectious Spleen and Kidney Necrosis Virus (ISKNV) Triggers Mitochondria-Mediated Dynamic Interaction Signals via an Imbalance of Bax/Bak over Bcl-2/Bcl-xL in Fish Cells

The molecular pathogenesis of infectious spleen and kidney necrosis virus (ISKNV) infections is important but has rarely been studied in connection to host organelle behavior. In the present study, we demonstrated that ISKNV can induce host cell death via a pro-apoptotic Bcl-2 and anti-apoptotic Bcl...

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Detalles Bibliográficos
Autores principales: Chen, Pin-Han, Hsueh, Tsai-Ching, Wu, Jen-Leih, Hong, Jiann-Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144193/
https://www.ncbi.nlm.nih.gov/pubmed/35632664
http://dx.doi.org/10.3390/v14050922