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The Pressure Dependence of the Stability of the G-quadruplex Formed by d(TGGGGT)

The G-quadruplex (GQ), a tetrahelix formed by guanine-rich nucleic acid sequences, is a potential drug target for several diseases. Monomolecular GQs are stabilized by guanine tetrads and non-guanine regions that form loops. Hydrostatic pressure destabilizes the folded, monomolecular GQ structures....

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Detalles Bibliográficos
Autores principales:	Tariq, Nabeel, Kume, Takuma, Feroze, Ujala N., Macgregor, Robert B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144232/ https://www.ncbi.nlm.nih.gov/pubmed/35629431 http://dx.doi.org/10.3390/life12050765

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