Rearrangement in the Hypervariable Region of JC Polyomavirus Genomes Isolated from Patient Samples and Impact on Transcription Factor-Binding Sites and Disease Outcomes

JC polyomavirus (JCPyV) is the causative agent of the fatal, incurable, neurological disease, progressive multifocal leukoencephalopathy (PML). The virus is present in most of the adult population as a persistent, asymptotic infection in the kidneys. During immunosuppression, JCPyV reactivates and i...

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Detalles Bibliográficos
Autores principales: Wilczek, Michael P., Pike, Aiden M. C., Craig, Sophie E., Maginnis, Melissa S., King, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144386/
https://www.ncbi.nlm.nih.gov/pubmed/35628509
http://dx.doi.org/10.3390/ijms23105699

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