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Influence of In Situ Calcium Pectinate Coating on Metoprolol Tartrate Pellets for Controlled Release and Colon-Specific Drug Delivery

In situ calcium pectinate-coated pellets were proposed by applying an alternate coating method to drug-layered pellets to achieve colon-specific drug delivery. Solution layering of metroprolol tartrate, a water-soluble model drug, on inert core pellets was achieved using a centrifugal granulator fol...

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Detalles Bibliográficos
Autores principales: Wanasawas, Pimphaka, Mitrevej, Ampol, Sinchaipanid, Nuttanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144396/
https://www.ncbi.nlm.nih.gov/pubmed/35631647
http://dx.doi.org/10.3390/pharmaceutics14051061