Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media

Treatment of the imines a–c with palladium(II) acetate in acetic acid yielded the μ-acetate dinuclear complexes 1a–c, which readily reacted with sodium chloride or bromide to provide μ-halide analogues. The reaction of the latter with nitrogen, phosphorus and oxygen donor nucleophiles yielded new im...

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Autores principales: Bermúdez-Puente, Brais, Adrio, Luis A., Lucio-Martínez, Fátima, Reigosa, Francisco, Ortigueira, Juan M., Vila, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144456/
https://www.ncbi.nlm.nih.gov/pubmed/35630622
http://dx.doi.org/10.3390/molecules27103146
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author Bermúdez-Puente, Brais
Adrio, Luis A.
Lucio-Martínez, Fátima
Reigosa, Francisco
Ortigueira, Juan M.
Vila, José M.
author_facet Bermúdez-Puente, Brais
Adrio, Luis A.
Lucio-Martínez, Fátima
Reigosa, Francisco
Ortigueira, Juan M.
Vila, José M.
author_sort Bermúdez-Puente, Brais
collection PubMed
description Treatment of the imines a–c with palladium(II) acetate in acetic acid yielded the μ-acetate dinuclear complexes 1a–c, which readily reacted with sodium chloride or bromide to provide μ-halide analogues. The reaction of the latter with nitrogen, phosphorus and oxygen donor nucleophiles yielded new imine palladacycles following the cleavage of the Pd(2)X(2) unit. The complexes were fully characterized by microanalysis, (1)H, (13)C and (31)P NMR spectroscopies, as appropriate. The compounds were applied as catalysts in the Suzuki–Miyaura coupling reaction in aqueous and semi-aqueous media.
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spelling pubmed-91444562022-05-29 Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media Bermúdez-Puente, Brais Adrio, Luis A. Lucio-Martínez, Fátima Reigosa, Francisco Ortigueira, Juan M. Vila, José M. Molecules Article Treatment of the imines a–c with palladium(II) acetate in acetic acid yielded the μ-acetate dinuclear complexes 1a–c, which readily reacted with sodium chloride or bromide to provide μ-halide analogues. The reaction of the latter with nitrogen, phosphorus and oxygen donor nucleophiles yielded new imine palladacycles following the cleavage of the Pd(2)X(2) unit. The complexes were fully characterized by microanalysis, (1)H, (13)C and (31)P NMR spectroscopies, as appropriate. The compounds were applied as catalysts in the Suzuki–Miyaura coupling reaction in aqueous and semi-aqueous media. MDPI 2022-05-14 /pmc/articles/PMC9144456/ /pubmed/35630622 http://dx.doi.org/10.3390/molecules27103146 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bermúdez-Puente, Brais
Adrio, Luis A.
Lucio-Martínez, Fátima
Reigosa, Francisco
Ortigueira, Juan M.
Vila, José M.
Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media
title Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media
title_full Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media
title_fullStr Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media
title_full_unstemmed Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media
title_short Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki–Miyaura Cross Coupling in Semi-Aqueous Media
title_sort imine palladacycles: synthesis, structural analysis and application in suzuki–miyaura cross coupling in semi-aqueous media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144456/
https://www.ncbi.nlm.nih.gov/pubmed/35630622
http://dx.doi.org/10.3390/molecules27103146
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