The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer’s Disease

Soluble amyloid β (Aβ) oligomers have been shown to be highly toxic to neurons and are considered to be a major cause of the neurodegeneration underlying Alzheimer’s disease (AD). That makes soluble Aβ oligomers a promising drug target. In addition to eliminating these toxic species from the patient...

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Detalles Bibliográficos
Autores principales: Russ, Hermann, Mazzanti, Michele, Parsons, Chris, Riemann, Katrin, Gebauer, Alexander, Rammes, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144469/
https://www.ncbi.nlm.nih.gov/pubmed/35628602
http://dx.doi.org/10.3390/ijms23105794

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