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Comparison of Paliperidone Palmitate from Different Crystallization Processes and Effect on Formulations In Vitro and In Vivo
The quality of active pharmaceutical ingredients (APIs) is an important factor which can affect the safety and efficacy of pharmaceuticals. This study was designed to investigate the nature of paliperidone palmitate (PP) obtained by different crystallization processes, then compare the characteristi...
Autores principales: | Shi, Junfeng, Wang, Dan, Tian, Yang, Wang, Zengming, Gao, Jing, Liu, Nan, Gao, Xiang, Zheng, Aiping, Zhang, Hui, Xiang, Meixian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144547/ https://www.ncbi.nlm.nih.gov/pubmed/35631680 http://dx.doi.org/10.3390/pharmaceutics14051094 |
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