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Relationship between Dietary Magnesium Intake and Metabolic Syndrome

Metabolic syndrome (MetS) is increasingly prevalent, and the relationship between dietary magnesium and MetS remains controversial. Therefore, we aimed to explore the association and dose-response relationship between dietary magnesium intake and MetS and its single component. The sample was adults...

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Autores principales: Jiao, Yingying, Li, Weiyi, Wang, Liusen, Jiang, Hongru, Wang, Shaoshunzi, Jia, Xiaofang, Wang, Zhihong, Wang, Huijun, Zhang, Bing, Ding, Gangqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144620/
https://www.ncbi.nlm.nih.gov/pubmed/35631154
http://dx.doi.org/10.3390/nu14102013
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author Jiao, Yingying
Li, Weiyi
Wang, Liusen
Jiang, Hongru
Wang, Shaoshunzi
Jia, Xiaofang
Wang, Zhihong
Wang, Huijun
Zhang, Bing
Ding, Gangqiang
author_facet Jiao, Yingying
Li, Weiyi
Wang, Liusen
Jiang, Hongru
Wang, Shaoshunzi
Jia, Xiaofang
Wang, Zhihong
Wang, Huijun
Zhang, Bing
Ding, Gangqiang
author_sort Jiao, Yingying
collection PubMed
description Metabolic syndrome (MetS) is increasingly prevalent, and the relationship between dietary magnesium and MetS remains controversial. Therefore, we aimed to explore the association and dose-response relationship between dietary magnesium intake and MetS and its single component. The sample was adults aged 18 years and above who participated in at least two follow-up surveys in 2009, 2015 and 2018. Food consumption data were collected from three consecutive 24-h dietary recalls. The multivariate Cox proportional risk regression model and restricted cubic spline (RCS) model were used to analyze the association and dose-response relationship between dietary magnesium intake and MetS and its components. In our study, 6104 subjects were included, with a total follow-up of 37,173.36 person-years, and the incidence was 33.16%. Cox regression analysis showed that the multivariable-adjusted Hazard Ratio (HR) for MetS comparing the highest to the lowest quintile of dietary magnesium intake was 0.84 (95% confidence intervals [CI] = 0.71–0.99). Central obesity, elevated TG, elevated blood pressure and elevated blood glucose were reduced by 18%, 41%, 20% and 42%, respectively. The risk of decreased HDL-C was reduced by 23% in the third quintile of dietary magnesium intake, with a slightly increased risk in the highest group. RCS analysis showed that the overall and non-linear associations between dietary magnesium and MetS and its components were statistically significant, the risk of them decreased significantly when magnesium intake was lower than 280 mg/day, and then the curve leveled off or slightly increased.
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spelling pubmed-91446202022-05-29 Relationship between Dietary Magnesium Intake and Metabolic Syndrome Jiao, Yingying Li, Weiyi Wang, Liusen Jiang, Hongru Wang, Shaoshunzi Jia, Xiaofang Wang, Zhihong Wang, Huijun Zhang, Bing Ding, Gangqiang Nutrients Article Metabolic syndrome (MetS) is increasingly prevalent, and the relationship between dietary magnesium and MetS remains controversial. Therefore, we aimed to explore the association and dose-response relationship between dietary magnesium intake and MetS and its single component. The sample was adults aged 18 years and above who participated in at least two follow-up surveys in 2009, 2015 and 2018. Food consumption data were collected from three consecutive 24-h dietary recalls. The multivariate Cox proportional risk regression model and restricted cubic spline (RCS) model were used to analyze the association and dose-response relationship between dietary magnesium intake and MetS and its components. In our study, 6104 subjects were included, with a total follow-up of 37,173.36 person-years, and the incidence was 33.16%. Cox regression analysis showed that the multivariable-adjusted Hazard Ratio (HR) for MetS comparing the highest to the lowest quintile of dietary magnesium intake was 0.84 (95% confidence intervals [CI] = 0.71–0.99). Central obesity, elevated TG, elevated blood pressure and elevated blood glucose were reduced by 18%, 41%, 20% and 42%, respectively. The risk of decreased HDL-C was reduced by 23% in the third quintile of dietary magnesium intake, with a slightly increased risk in the highest group. RCS analysis showed that the overall and non-linear associations between dietary magnesium and MetS and its components were statistically significant, the risk of them decreased significantly when magnesium intake was lower than 280 mg/day, and then the curve leveled off or slightly increased. MDPI 2022-05-11 /pmc/articles/PMC9144620/ /pubmed/35631154 http://dx.doi.org/10.3390/nu14102013 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jiao, Yingying
Li, Weiyi
Wang, Liusen
Jiang, Hongru
Wang, Shaoshunzi
Jia, Xiaofang
Wang, Zhihong
Wang, Huijun
Zhang, Bing
Ding, Gangqiang
Relationship between Dietary Magnesium Intake and Metabolic Syndrome
title Relationship between Dietary Magnesium Intake and Metabolic Syndrome
title_full Relationship between Dietary Magnesium Intake and Metabolic Syndrome
title_fullStr Relationship between Dietary Magnesium Intake and Metabolic Syndrome
title_full_unstemmed Relationship between Dietary Magnesium Intake and Metabolic Syndrome
title_short Relationship between Dietary Magnesium Intake and Metabolic Syndrome
title_sort relationship between dietary magnesium intake and metabolic syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144620/
https://www.ncbi.nlm.nih.gov/pubmed/35631154
http://dx.doi.org/10.3390/nu14102013
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