Cargando…
Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children
Insulin resistance (IR) is a key component in the etiopathogenesis of hypertension (HS) in patients with diabetes mellitus (DM). Several pathways have been found to be involved in this mechanism in recent literature. For the above-mentioned reasons, treatment of HS should be specifically addressed i...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144705/ https://www.ncbi.nlm.nih.gov/pubmed/35628624 http://dx.doi.org/10.3390/ijms23105814 |
_version_ | 1784716113484972032 |
---|---|
author | Tagi, Veronica Maria Mainieri, Francesca Chiarelli, Francesco |
author_facet | Tagi, Veronica Maria Mainieri, Francesca Chiarelli, Francesco |
author_sort | Tagi, Veronica Maria |
collection | PubMed |
description | Insulin resistance (IR) is a key component in the etiopathogenesis of hypertension (HS) in patients with diabetes mellitus (DM). Several pathways have been found to be involved in this mechanism in recent literature. For the above-mentioned reasons, treatment of HS should be specifically addressed in patients affected by DM. Two relevant recently published guidelines have stressed this concept, giving specific advice in the treatment of HS in children belonging to this group: the European Society of HS guidelines for the management of high blood pressure in children and adolescents and the American Academy of Pediatrics Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents. Our aim is to summarize the main pathophysiological mechanisms through which IR causes HS and to highlight the specific principles of treatment of HS for children with DM. |
format | Online Article Text |
id | pubmed-9144705 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91447052022-05-29 Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children Tagi, Veronica Maria Mainieri, Francesca Chiarelli, Francesco Int J Mol Sci Review Insulin resistance (IR) is a key component in the etiopathogenesis of hypertension (HS) in patients with diabetes mellitus (DM). Several pathways have been found to be involved in this mechanism in recent literature. For the above-mentioned reasons, treatment of HS should be specifically addressed in patients affected by DM. Two relevant recently published guidelines have stressed this concept, giving specific advice in the treatment of HS in children belonging to this group: the European Society of HS guidelines for the management of high blood pressure in children and adolescents and the American Academy of Pediatrics Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents. Our aim is to summarize the main pathophysiological mechanisms through which IR causes HS and to highlight the specific principles of treatment of HS for children with DM. MDPI 2022-05-22 /pmc/articles/PMC9144705/ /pubmed/35628624 http://dx.doi.org/10.3390/ijms23105814 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Tagi, Veronica Maria Mainieri, Francesca Chiarelli, Francesco Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children |
title | Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children |
title_full | Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children |
title_fullStr | Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children |
title_full_unstemmed | Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children |
title_short | Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children |
title_sort | hypertension in patients with insulin resistance: etiopathogenesis and management in children |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144705/ https://www.ncbi.nlm.nih.gov/pubmed/35628624 http://dx.doi.org/10.3390/ijms23105814 |
work_keys_str_mv | AT tagiveronicamaria hypertensioninpatientswithinsulinresistanceetiopathogenesisandmanagementinchildren AT mainierifrancesca hypertensioninpatientswithinsulinresistanceetiopathogenesisandmanagementinchildren AT chiarellifrancesco hypertensioninpatientswithinsulinresistanceetiopathogenesisandmanagementinchildren |