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Seizures in PPT1 Knock-In Mice Are Associated with Inflammatory Activation of Microglia

Infantile neuronal ceroid lipofuscinosis (INCL), the most severe form of neuronal ceroid lipofuscinoses, is caused by mutations in the lysosomal enzyme palmitoyl protein thioesterase 1 (PPT1). Typical symptoms of this disease include progressive psychomotor developmental retardation, visual failure,...

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Detalles Bibliográficos
Autores principales:	Zhang, Xusheng, Wang, Mengting, Feng, Bingyan, Zhang, Qiuyu, Tong, Jia, Wang, Mingyong, Lu, Chengbiao, Peng, Shiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144763/ https://www.ncbi.nlm.nih.gov/pubmed/35628400 http://dx.doi.org/10.3390/ijms23105586

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