Cargando…

Modulation of Signal Regulatory Protein α (SIRPα) by Plasmodium Antigenic Extract: A Preliminary In Vitro Study on Peripheral Blood Mononuclear Cells

Signal regulatory protein α (SIRPα) is an immunoreceptor expressed in myeloid innate immune cells that signals for inhibition of both phagocytosis and inflammatory response. Malaria parasites have evolutionarily selected multiple mechanisms that allow them to evade host immune defenses, including th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martins, Priscilla da Costa, de Souza, Hugo Amorim dos Santos, Blanco, Carolina Moreira, Santos-de-Oliveira, Luana, Pratt-Riccio, Lilian Rose, Daniel-Ribeiro, Cláudio Tadeu, Totino, Paulo Renato Rivas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144821/ https://www.ncbi.nlm.nih.gov/pubmed/35630348 http://dx.doi.org/10.3390/microorganisms10050903

Ejemplares similares

Detection of Signal Regulatory Protein α in Saimiri sciureus (Squirrel Monkey) by Anti-Human Monoclonal Antibody
por: de Souza, Hugo Amorim dos Santos, et al.
Publicado: (2017)

B-Cell Epitope Mapping of the Plasmodium falciparum Malaria Vaccine Candidate GMZ2.6c in a Naturally Exposed Population of the Brazilian Amazon
por: Baptista, Barbara de Oliveira, et al.
Publicado: (2023)

Construction, Expression, and Evaluation of the Naturally Acquired Humoral Immune Response against Plasmodium vivax RMC-1, a Multistage Chimeric Protein
por: Matos, Ada da Silva, et al.
Publicado: (2023)

Targeting SIRPα in cancer
por: Ho, Jenny M., et al.
Publicado: (2013)

Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon
por: de Souza, Hugo Amorim dos Santos, et al.
Publicado: (2021)

Cellular and humoral immune responses against the Plasmodium vivax MSP-1(19) malaria vaccine candidate in individuals living in a Brazilian endemic area in northeastern Amazon
por: Riccio, Evelyn Kety Pratt, et al.
Publicado: (2014)

Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα–CD47 innate immune checkpoint
por: Voets, Erik, et al.
Publicado: (2019)

Anticancer efficacy of monotherapy with antibodies to SIRPα/SIRPβ1 mediated by induction of antitumorigenic macrophages
por: Sakamoto, Mariko, et al.
Publicado: (2021)

Cancer Therapy Targeting CD47/SIRPα
por: Dizman, Nazli, et al.
Publicado: (2021)

Refractoriness of Eryptotic Red Blood Cells to Plasmodium falciparum Infection: A Putative Host Defense Mechanism Limiting Parasitaemia
por: Totino, Paulo Renato Rivas, et al.
Publicado: (2011)

Genetic Diversity of Plasmodium vivax Cysteine-Rich Protective Antigen (PvCyRPA) in Field Isolates from Five Different Areas of the Brazilian Amazon
por: Bitencourt Chaves, Lana, et al.
Publicado: (2021)

Synapse Maturation by Activity-Dependent Ectodomain Shedding of SIRPα
por: Toth, Anna B., et al.
Publicado: (2013)

The SIRPα–CD47 immune checkpoint in NK cells
por: Deuse, Tobias, et al.
Publicado: (2021)

CD47–SIRPα-targeted therapeutics: status and prospects
por: Maute, R., et al.
Publicado: (2022)

Leishmania Infection-Induced Proteolytic Processing of SIRPα in Macrophages
por: Hirai, Hana, et al.
Publicado: (2023)

Membrane-Mediated Cooperative Interactions of CD47 and SIRPα
por: Li, Long, et al.
Publicado: (2023)

Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areas
por: Baptista, Barbara Oliveira, et al.
Publicado: (2022)

Cellular and humoral immune responses against the Plasmodium vivax MSP-1(19) malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil
por: Riccio, Evelyn KP, et al.
Publicado: (2013)

BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells
por: van Helden, Mary J, et al.
Publicado: (2023)

OX130 Monoclonal Antibody Recognizes Human SIRPβ1 but Cross-Reacts on SIRPα from One Allele
por: Hatherley, Deborah, et al.
Publicado: (2016)

Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth
por: De Marco, Margot, et al.
Publicado: (2022)

Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon
por: Pratt-Riccio, Lilian Rose, et al.
Publicado: (2019)

SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells
por: Nuvolone, Mario, et al.
Publicado: (2013)

The Immunotherapeutic Effect of SIRPα-Silenced DCs against Cervical Cancer
por: Li, Xiaojie, et al.
Publicado: (2020)

Insights into CD47/SIRPα axis-targeting tumor immunotherapy
por: Zhang, Xuyao, et al.
Publicado: (2018)

CD47/SIRPα axis: bridging innate and adaptive immunity
por: van Duijn, Anneloes, et al.
Publicado: (2022)

Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis
por: Okamoto, Takeshi, et al.
Publicado: (2023)

SIRPα blockade improves the antitumor immunity of radiotherapy in colorectal cancer
por: Ji, Kai, et al.
Publicado: (2023)

Antibody Responses Against Plasmodium vivax TRAP Recombinant and Synthetic Antigens in Naturally Exposed Individuals From the Brazilian Amazon
por: Matos, Ada da Silva, et al.
Publicado: (2019)

Major Histocompatibility Complex and Malaria: Focus on Plasmodium vivax Infection
por: Lima-Junior, Josué da Costa, et al.
Publicado: (2016)

Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants
por: Weiskopf, Kipp, et al.
Publicado: (2013)

Anti‐human SIRPα antibody is a new tool for cancer immunotherapy
por: Murata, Yoji, et al.
Publicado: (2018)

Potential New Cancer Immunotherapy: Anti-CD47-SIRPα Antibodies
por: Lu, Quansheng, et al.
Publicado: (2020)

Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis
por: Zhang, Wenting, et al.
Publicado: (2020)

MICROGLIA MAY INSTRUCT SYNAPTIC FATE VIA SIRPα IN MOUSE RETINA
por: Jiang, Danye, et al.
Publicado: (2019)

Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration
por: Ding, Xin, et al.
Publicado: (2021)

CD47/SIRPα pathway mediates cancer immune escape and immunotherapy
por: Jia, Xiao, et al.
Publicado: (2021)

Molecular and immunological tools for the evaluation of the cellular immune response in the neotropical monkey Saimiri sciureus, a non-human primate model for malaria research
por: Riccio, Evelyn KP, et al.
Publicado: (2015)

SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production
por: Franke, Katka, et al.
Publicado: (2020)

Recombinant Plasmodium vivax circumsporozoite surface protein allelic variants: antibody recognition by individuals from three communities in the Brazilian Amazon
por: Soares, Isabela Ferreira, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b5v7gn0lq54dd3267p21qafan9