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Formulation and Biological Evaluation of Mesoporous Silica Nanoparticles Loaded with Combinations of Sortase A Inhibitors and Antimicrobial Peptides

This study aimed to develop synergistic therapies to treat superbug infections through the encapsulation of sortase A inhibitors (SrtAIs; trans-chalcone (TC), curcumin (CUR), quercetin (QC), or berberine chloride (BR)) into MCM-41 mesoporous silica nanoparticles (MSNs) or a phosphonate-modified anal...

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Detalles Bibliográficos
Autores principales: Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali, Moyle, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144937/
https://www.ncbi.nlm.nih.gov/pubmed/35631572
http://dx.doi.org/10.3390/pharmaceutics14050986