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A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality
There is little evidence for the association between fruit juice, especially 100% fruit juice, and mortality risk. In addition, whether 100% fruit juice can be a healthy alternative to whole fruit remains uncertain. This prospective study utilized the data from the US National Health and Nutrition E...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144949/ https://www.ncbi.nlm.nih.gov/pubmed/35631268 http://dx.doi.org/10.3390/nu14102127 |
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author | Zhang, Zhuang Zeng, Xueke Li, Meiling Zhang, Tengfei Li, Haowei Yang, Hu Huang, Yong Zhu, Yu Li, Xiude Yang, Wanshui |
author_facet | Zhang, Zhuang Zeng, Xueke Li, Meiling Zhang, Tengfei Li, Haowei Yang, Hu Huang, Yong Zhu, Yu Li, Xiude Yang, Wanshui |
author_sort | Zhang, Zhuang |
collection | PubMed |
description | There is little evidence for the association between fruit juice, especially 100% fruit juice, and mortality risk. In addition, whether 100% fruit juice can be a healthy alternative to whole fruit remains uncertain. This prospective study utilized the data from the US National Health and Nutrition Examination Survey (NHANES) from 1999 to 2014. After a median follow-up of 7.8 years, 4904 deaths among 40,074 participants aged 18 years or older were documented. Compared to non-consumption, daily consumption of 250 g or more of 100% fruit juice was associated with higher overall mortality (hazard ratio (HR) = 1.30, 95% confidence interval (CI): 1.11–1.52) and mortality from heart disease (HR = 1.49, 95 CI: 1.01–2.21). A similar pattern was observed for total fruit juice, with HRs of 1.28 (95% CI: 1.09–1.49) for overall mortality and 1.48 (95% CI: 1.01–2.17) for heart disease mortality. Replacing 5% of energy from whole fruit with 100% or total fruit juice was associated with a 9% (95% CI: 2–16%) and 8% (95% CI: 1–15%) increased mortality risk, respectively. Our findings suggest that both total and 100% fruit juice could be associated with high mortality risk, and need to be validated in well-designed studies given the potential misclassification of diet and death reasons. |
format | Online Article Text |
id | pubmed-9144949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91449492022-05-29 A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality Zhang, Zhuang Zeng, Xueke Li, Meiling Zhang, Tengfei Li, Haowei Yang, Hu Huang, Yong Zhu, Yu Li, Xiude Yang, Wanshui Nutrients Article There is little evidence for the association between fruit juice, especially 100% fruit juice, and mortality risk. In addition, whether 100% fruit juice can be a healthy alternative to whole fruit remains uncertain. This prospective study utilized the data from the US National Health and Nutrition Examination Survey (NHANES) from 1999 to 2014. After a median follow-up of 7.8 years, 4904 deaths among 40,074 participants aged 18 years or older were documented. Compared to non-consumption, daily consumption of 250 g or more of 100% fruit juice was associated with higher overall mortality (hazard ratio (HR) = 1.30, 95% confidence interval (CI): 1.11–1.52) and mortality from heart disease (HR = 1.49, 95 CI: 1.01–2.21). A similar pattern was observed for total fruit juice, with HRs of 1.28 (95% CI: 1.09–1.49) for overall mortality and 1.48 (95% CI: 1.01–2.17) for heart disease mortality. Replacing 5% of energy from whole fruit with 100% or total fruit juice was associated with a 9% (95% CI: 2–16%) and 8% (95% CI: 1–15%) increased mortality risk, respectively. Our findings suggest that both total and 100% fruit juice could be associated with high mortality risk, and need to be validated in well-designed studies given the potential misclassification of diet and death reasons. MDPI 2022-05-19 /pmc/articles/PMC9144949/ /pubmed/35631268 http://dx.doi.org/10.3390/nu14102127 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Zhuang Zeng, Xueke Li, Meiling Zhang, Tengfei Li, Haowei Yang, Hu Huang, Yong Zhu, Yu Li, Xiude Yang, Wanshui A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality |
title | A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality |
title_full | A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality |
title_fullStr | A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality |
title_full_unstemmed | A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality |
title_short | A Prospective Study of Fruit Juice Consumption and the Risk of Overall and Cardiovascular Disease Mortality |
title_sort | prospective study of fruit juice consumption and the risk of overall and cardiovascular disease mortality |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144949/ https://www.ncbi.nlm.nih.gov/pubmed/35631268 http://dx.doi.org/10.3390/nu14102127 |
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