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Psychosocial Burden of Itch among Renal Transplant Recipients
Itch is the most common symptom of chronic dermatoses. Moreover, itch may be associated with systemic disorders. Chronic kidney disease—associated itch (CKD-aI) may affect up to 20% of renal transplant recipients (RTR). The aim of the study was to assess psychosocial burden of itch in RTR. The study...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145006/ https://www.ncbi.nlm.nih.gov/pubmed/35622567 http://dx.doi.org/10.3390/toxins14050320 |
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author | Krajewski, Piotr K. Tyczyńska, Kinga Bardowska, Klaudia Olczyk, Piotr Krajewska, Magdalena Szepietowski, Jacek C. |
author_facet | Krajewski, Piotr K. Tyczyńska, Kinga Bardowska, Klaudia Olczyk, Piotr Krajewska, Magdalena Szepietowski, Jacek C. |
author_sort | Krajewski, Piotr K. |
collection | PubMed |
description | Itch is the most common symptom of chronic dermatoses. Moreover, itch may be associated with systemic disorders. Chronic kidney disease—associated itch (CKD-aI) may affect up to 20% of renal transplant recipients (RTR). The aim of the study was to assess psychosocial burden of itch in RTR. The study was performed on a group of 129 RTR, out of which 54 (41.9%) experienced itch in the previous 3 days. A specially designed questionnaire assessing anxiety, depression, stigmatization, and quality of life was used. Results: Patients suffering from itch in the previous 3 days achieved significantly higher scores in GAD-7 (p < 0.001), BDI (p < 0.001), HADS total score (p < 0.001), HADS Depression (p = 0.004), and HADS Anxiety (p < 0.001). Severity of itch correlated positively with HADS, stigmatization scale, and GAD-7. Itch in RTR was associated with higher incidence of depression assessed with BDI (OR 3.7). Moreover, higher prevalence of anxiety was found among patients suffering from CKD-aI, assessed with HADS A and GAD-7 (OR 2.7 and OR 4.8, respectively) The results of our study clearly demonstrate that itch among RTR is a significant burden. Higher prevalence of depression and anxiety in this groups indicate the necessity of addressing itch relief as a part of holistic approach to patients after renal transplantation. |
format | Online Article Text |
id | pubmed-9145006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91450062022-05-29 Psychosocial Burden of Itch among Renal Transplant Recipients Krajewski, Piotr K. Tyczyńska, Kinga Bardowska, Klaudia Olczyk, Piotr Krajewska, Magdalena Szepietowski, Jacek C. Toxins (Basel) Article Itch is the most common symptom of chronic dermatoses. Moreover, itch may be associated with systemic disorders. Chronic kidney disease—associated itch (CKD-aI) may affect up to 20% of renal transplant recipients (RTR). The aim of the study was to assess psychosocial burden of itch in RTR. The study was performed on a group of 129 RTR, out of which 54 (41.9%) experienced itch in the previous 3 days. A specially designed questionnaire assessing anxiety, depression, stigmatization, and quality of life was used. Results: Patients suffering from itch in the previous 3 days achieved significantly higher scores in GAD-7 (p < 0.001), BDI (p < 0.001), HADS total score (p < 0.001), HADS Depression (p = 0.004), and HADS Anxiety (p < 0.001). Severity of itch correlated positively with HADS, stigmatization scale, and GAD-7. Itch in RTR was associated with higher incidence of depression assessed with BDI (OR 3.7). Moreover, higher prevalence of anxiety was found among patients suffering from CKD-aI, assessed with HADS A and GAD-7 (OR 2.7 and OR 4.8, respectively) The results of our study clearly demonstrate that itch among RTR is a significant burden. Higher prevalence of depression and anxiety in this groups indicate the necessity of addressing itch relief as a part of holistic approach to patients after renal transplantation. MDPI 2022-04-30 /pmc/articles/PMC9145006/ /pubmed/35622567 http://dx.doi.org/10.3390/toxins14050320 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Krajewski, Piotr K. Tyczyńska, Kinga Bardowska, Klaudia Olczyk, Piotr Krajewska, Magdalena Szepietowski, Jacek C. Psychosocial Burden of Itch among Renal Transplant Recipients |
title | Psychosocial Burden of Itch among Renal Transplant Recipients |
title_full | Psychosocial Burden of Itch among Renal Transplant Recipients |
title_fullStr | Psychosocial Burden of Itch among Renal Transplant Recipients |
title_full_unstemmed | Psychosocial Burden of Itch among Renal Transplant Recipients |
title_short | Psychosocial Burden of Itch among Renal Transplant Recipients |
title_sort | psychosocial burden of itch among renal transplant recipients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145006/ https://www.ncbi.nlm.nih.gov/pubmed/35622567 http://dx.doi.org/10.3390/toxins14050320 |
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