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Brain-Targeted Intranasal Delivery of Zotepine Microemulsion: Pharmacokinetics and Pharmacodynamics

The purpose of our study was to improve the solubility, bioavailability, and efficacy of zotepine (ZTP) by brain-targeted intranasal delivery of microemulsion (ME) and its physicochemical properties, the pharmacokinetic and pharmacodynamic parameters were evaluated. The optimized ME formulations con...

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Detalles Bibliográficos
Autores principales:	Pailla, Sravanthi Reddy, Sampathi, Sunitha, Junnuthula, Vijayabhaskarreddy, Maddukuri, Sravya, Dodoala, Sujatha, Dyawanapelly, Sathish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145021/ https://www.ncbi.nlm.nih.gov/pubmed/35631564 http://dx.doi.org/10.3390/pharmaceutics14050978

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