CXCL13 expressed on inflamed cerebral blood vessels recruit IL-21 producing T(FH) cells to damage neurons following stroke

BACKGROUND: Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved drugs targeting the inflammatory component to stroke. Prec...

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Detalles Bibliográficos
Autores principales: Rayasam, Aditya, Kijak, Julie A., Kissel, Lee, Choi, Yun Hwa, Kim, Taehee, Hsu, Martin, Joshi, Dinesh, Laaker, Collin J., Cismaru, Peter, Lindstedt, Anders, Kovacs, Krisztian, Vemuganti, Raghu, Chiu, Shing Yan, Priyathilaka, Thanthrige Thiunuwan, Sandor, Matyas, Fabry, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145182/
https://www.ncbi.nlm.nih.gov/pubmed/35624463
http://dx.doi.org/10.1186/s12974-022-02490-2

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