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Obeticholic Acid Reduces Kidney Matrix Metalloproteinase Activation Following Partial Hepatic Ischemia/Reperfusion Injury in Rats

We have previously demonstrated that the farnesoid X receptor (FXR) agonist obeticholic acid (OCA) protects the liver via downregulation of hepatic matrix metalloproteinases (MMPs) after ischemia/reperfusion (I/R), which can lead to multiorgan dysfunction. The present study investigated the capacity...

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Detalles Bibliográficos
Autores principales:	Palladini, Giuseppina, Cagna, Marta, Di Pasqua, Laura Giuseppina, Adorini, Luciano, Croce, Anna Cleta, Perlini, Stefano, Ferrigno, Andrea, Berardo, Clarissa, Vairetti, Mariapia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145209/ https://www.ncbi.nlm.nih.gov/pubmed/35631351 http://dx.doi.org/10.3390/ph15050524

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