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Lactate Neuroprotection against Transient Ischemic Brain Injury in Mice Appears Independent of HCAR1 Activation
Lactate can protect against damage caused by acute brain injuries both in rodents and in human patients. Besides its role as a metabolic support and alleged preferred neuronal fuel in stressful situations, an additional signaling mechanism mediated by the hydroxycarboxylic acid receptor 1 (HCAR1) wa...
Autores principales: | Buscemi, Lara, Price, Melanie, Castillo-González, Julia, Chatton, Jean-Yves, Hirt, Lorenz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145226/ https://www.ncbi.nlm.nih.gov/pubmed/35629969 http://dx.doi.org/10.3390/metabo12050465 |
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