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Development of a Promising (18)F-Radiotracer for PET Imaging Legumain Activity In Vivo
Legumain has been found overexpressed in several cancers, which serves as an important biomarker for cancer diagnosis. In this research, a novel fluorine-18 labeled radioactive tracer [(18)F]SF-AAN targeting legumain was designed and synthesized for positron emission tomography (PET) imaging. Nonrad...
Autores principales: | Lu, Chunmei, Wang, Xiuting, Wang, Qiqi, Zhang, Lixia, Lin, Jianguo, Qiu, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145320/ https://www.ncbi.nlm.nih.gov/pubmed/35631369 http://dx.doi.org/10.3390/ph15050543 |
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