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Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment. In this study, we hypothesized that combining DNA vaccines—to stimulate a specific immune response—and dua...

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Detalles Bibliográficos
Autores principales:	Bausart, Mathilde, Vanvarenberg, Kevin, Ucakar, Bernard, Lopes, Alessandra, Vandermeulen, Gaëlle, Malfanti, Alessio, Préat, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145362/ https://www.ncbi.nlm.nih.gov/pubmed/35631612 http://dx.doi.org/10.3390/pharmaceutics14051025

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