Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model

Evidence of the impact of nutrition on human brain development is compelling. Previous in vitro and in vivo results show that three specific amino acids, histidine, lysine, and threonine, synergistically inhibit mTOR activity and behavior. Therefore, the prenatal availability of these amino acids co...

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Detalles Bibliográficos
Autores principales: Berdenis van Berlekom, Amber, Kübler, Raphael, Hoogeboom, Jeske W., Vonk, Daniëlle, Sluijs, Jacqueline A., Pasterkamp, R. Jeroen, Middeldorp, Jinte, Kraneveld, Aletta D., Garssen, Johan, Kahn, René S., Hol, Elly M., de Witte, Lot D., Boks, Marco P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145399/
https://www.ncbi.nlm.nih.gov/pubmed/35631316
http://dx.doi.org/10.3390/nu14102175

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