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Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes

Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous temperature range for routine use in CPB. To addre...

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Autores principales: Haider, Adnan, Khwaja, Irfan Azmatullah, Qureshi, Abdul Basit, Khan, Imran, Majeed, Khalid Abdul, Yousaf, Muhammad Shahbaz, Zaneb, Hafsa, Rehman, Abdul, Rabbani, Imtiaz, Tahir, Sajid Khan, Rehman, Habib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145413/
https://www.ncbi.nlm.nih.gov/pubmed/35621862
http://dx.doi.org/10.3390/jcdd9050151
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author Haider, Adnan
Khwaja, Irfan Azmatullah
Qureshi, Abdul Basit
Khan, Imran
Majeed, Khalid Abdul
Yousaf, Muhammad Shahbaz
Zaneb, Hafsa
Rehman, Abdul
Rabbani, Imtiaz
Tahir, Sajid Khan
Rehman, Habib
author_facet Haider, Adnan
Khwaja, Irfan Azmatullah
Qureshi, Abdul Basit
Khan, Imran
Majeed, Khalid Abdul
Yousaf, Muhammad Shahbaz
Zaneb, Hafsa
Rehman, Abdul
Rabbani, Imtiaz
Tahir, Sajid Khan
Rehman, Habib
author_sort Haider, Adnan
collection PubMed
description Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous temperature range for routine use in CPB. To address this issue, we conducted a retrospective observational study to compare the effects of different hypothermic temperature ranges on primary (inotropic support, blood loss, and platelet count) and secondary (ventilation support and in-hospital stay) outcomes in patients undergoing elective cardiac surgery. Methods: Data were retrieved from the medical database of the Cardiovascular Surgery Department, King Edward Medical University, Lahore-Pakistan (a tertiary care hospital), dating from February 2015 to December 2017. Patients were divided into mild (34 °C to 36 °C), intermediate (31 °C to 33 °C), or moderate (28 °C to 30 °C) hypothermic groups. Results: Out of 275 patients, 245 (89.09%) fit the inclusion criteria. The cohort with mild hypothermic CPB temperatures presented better clinical outcomes in terms of requiring less inotropic support, less blood loss, fewer blood transfusions, improved platelet counts, shorter in-hospital stays, and required less ventilation support, when compared with other hypothermic groups. Conclusions: Mild hypothermic CPB (34 °C to 36 °C) may produce better clinical outcomes for cardiac surgery and improve the quality of health of cardiac patients.
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spelling pubmed-91454132022-05-29 Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes Haider, Adnan Khwaja, Irfan Azmatullah Qureshi, Abdul Basit Khan, Imran Majeed, Khalid Abdul Yousaf, Muhammad Shahbaz Zaneb, Hafsa Rehman, Abdul Rabbani, Imtiaz Tahir, Sajid Khan Rehman, Habib J Cardiovasc Dev Dis Article Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous temperature range for routine use in CPB. To address this issue, we conducted a retrospective observational study to compare the effects of different hypothermic temperature ranges on primary (inotropic support, blood loss, and platelet count) and secondary (ventilation support and in-hospital stay) outcomes in patients undergoing elective cardiac surgery. Methods: Data were retrieved from the medical database of the Cardiovascular Surgery Department, King Edward Medical University, Lahore-Pakistan (a tertiary care hospital), dating from February 2015 to December 2017. Patients were divided into mild (34 °C to 36 °C), intermediate (31 °C to 33 °C), or moderate (28 °C to 30 °C) hypothermic groups. Results: Out of 275 patients, 245 (89.09%) fit the inclusion criteria. The cohort with mild hypothermic CPB temperatures presented better clinical outcomes in terms of requiring less inotropic support, less blood loss, fewer blood transfusions, improved platelet counts, shorter in-hospital stays, and required less ventilation support, when compared with other hypothermic groups. Conclusions: Mild hypothermic CPB (34 °C to 36 °C) may produce better clinical outcomes for cardiac surgery and improve the quality of health of cardiac patients. MDPI 2022-05-09 /pmc/articles/PMC9145413/ /pubmed/35621862 http://dx.doi.org/10.3390/jcdd9050151 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Haider, Adnan
Khwaja, Irfan Azmatullah
Qureshi, Abdul Basit
Khan, Imran
Majeed, Khalid Abdul
Yousaf, Muhammad Shahbaz
Zaneb, Hafsa
Rehman, Abdul
Rabbani, Imtiaz
Tahir, Sajid Khan
Rehman, Habib
Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
title Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
title_full Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
title_fullStr Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
title_full_unstemmed Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
title_short Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
title_sort effectiveness of mild to moderate hypothermic cardiopulmonary bypass on early clinical outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145413/
https://www.ncbi.nlm.nih.gov/pubmed/35621862
http://dx.doi.org/10.3390/jcdd9050151
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