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Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes
Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous temperature range for routine use in CPB. To addre...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145413/ https://www.ncbi.nlm.nih.gov/pubmed/35621862 http://dx.doi.org/10.3390/jcdd9050151 |
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author | Haider, Adnan Khwaja, Irfan Azmatullah Qureshi, Abdul Basit Khan, Imran Majeed, Khalid Abdul Yousaf, Muhammad Shahbaz Zaneb, Hafsa Rehman, Abdul Rabbani, Imtiaz Tahir, Sajid Khan Rehman, Habib |
author_facet | Haider, Adnan Khwaja, Irfan Azmatullah Qureshi, Abdul Basit Khan, Imran Majeed, Khalid Abdul Yousaf, Muhammad Shahbaz Zaneb, Hafsa Rehman, Abdul Rabbani, Imtiaz Tahir, Sajid Khan Rehman, Habib |
author_sort | Haider, Adnan |
collection | PubMed |
description | Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous temperature range for routine use in CPB. To address this issue, we conducted a retrospective observational study to compare the effects of different hypothermic temperature ranges on primary (inotropic support, blood loss, and platelet count) and secondary (ventilation support and in-hospital stay) outcomes in patients undergoing elective cardiac surgery. Methods: Data were retrieved from the medical database of the Cardiovascular Surgery Department, King Edward Medical University, Lahore-Pakistan (a tertiary care hospital), dating from February 2015 to December 2017. Patients were divided into mild (34 °C to 36 °C), intermediate (31 °C to 33 °C), or moderate (28 °C to 30 °C) hypothermic groups. Results: Out of 275 patients, 245 (89.09%) fit the inclusion criteria. The cohort with mild hypothermic CPB temperatures presented better clinical outcomes in terms of requiring less inotropic support, less blood loss, fewer blood transfusions, improved platelet counts, shorter in-hospital stays, and required less ventilation support, when compared with other hypothermic groups. Conclusions: Mild hypothermic CPB (34 °C to 36 °C) may produce better clinical outcomes for cardiac surgery and improve the quality of health of cardiac patients. |
format | Online Article Text |
id | pubmed-9145413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91454132022-05-29 Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes Haider, Adnan Khwaja, Irfan Azmatullah Qureshi, Abdul Basit Khan, Imran Majeed, Khalid Abdul Yousaf, Muhammad Shahbaz Zaneb, Hafsa Rehman, Abdul Rabbani, Imtiaz Tahir, Sajid Khan Rehman, Habib J Cardiovasc Dev Dis Article Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous temperature range for routine use in CPB. To address this issue, we conducted a retrospective observational study to compare the effects of different hypothermic temperature ranges on primary (inotropic support, blood loss, and platelet count) and secondary (ventilation support and in-hospital stay) outcomes in patients undergoing elective cardiac surgery. Methods: Data were retrieved from the medical database of the Cardiovascular Surgery Department, King Edward Medical University, Lahore-Pakistan (a tertiary care hospital), dating from February 2015 to December 2017. Patients were divided into mild (34 °C to 36 °C), intermediate (31 °C to 33 °C), or moderate (28 °C to 30 °C) hypothermic groups. Results: Out of 275 patients, 245 (89.09%) fit the inclusion criteria. The cohort with mild hypothermic CPB temperatures presented better clinical outcomes in terms of requiring less inotropic support, less blood loss, fewer blood transfusions, improved platelet counts, shorter in-hospital stays, and required less ventilation support, when compared with other hypothermic groups. Conclusions: Mild hypothermic CPB (34 °C to 36 °C) may produce better clinical outcomes for cardiac surgery and improve the quality of health of cardiac patients. MDPI 2022-05-09 /pmc/articles/PMC9145413/ /pubmed/35621862 http://dx.doi.org/10.3390/jcdd9050151 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Haider, Adnan Khwaja, Irfan Azmatullah Qureshi, Abdul Basit Khan, Imran Majeed, Khalid Abdul Yousaf, Muhammad Shahbaz Zaneb, Hafsa Rehman, Abdul Rabbani, Imtiaz Tahir, Sajid Khan Rehman, Habib Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes |
title | Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes |
title_full | Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes |
title_fullStr | Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes |
title_full_unstemmed | Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes |
title_short | Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes |
title_sort | effectiveness of mild to moderate hypothermic cardiopulmonary bypass on early clinical outcomes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145413/ https://www.ncbi.nlm.nih.gov/pubmed/35621862 http://dx.doi.org/10.3390/jcdd9050151 |
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