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Poloxamer-188 Adjuvant Efficiently Maintains Adaptive Immunity of SARS-CoV-2 RBD Subunit Vaccination through Repressing p38MAPK Signaling

Poloxamer-188 (P188) is a nonionic triblock linear copolymer that can be used as a pharmaceutical excipient because of its amphiphilic nature. This study investigated whether P188 can act as an adjuvant to improve the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rec...

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Detalles Bibliográficos
Autores principales:	Chen, Chao-Hung, Lin, Yu-Jen, Cheng, Li-Ting, Lin, Chien-Hung, Ke, Guan-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145454/ https://www.ncbi.nlm.nih.gov/pubmed/35632471 http://dx.doi.org/10.3390/vaccines10050715

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