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miR-155 exerts posttranscriptional control of autoimmune regulator (Aire) and tissue-restricted antigen genes in medullary thymic epithelial cells
BACKGROUND: The autoimmune regulator (Aire) gene is critical for the appropriate establishment of central immune tolerance. As one of the main controllers of promiscuous gene expression in the thymus, Aire promotes the expression of thousands of downstream tissue-restricted antigen (TRA) genes, cell...
Autores principales: | Tanaka, Pedro Paranhos, Oliveira, Ernna Hérida, Vieira-Machado, Mayara Cristina, Duarte, Max Jordan, Assis, Amanda Freire, Bombonato-Prado, Karina Fittipaldi, Passos, Geraldo Aleixo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145475/ https://www.ncbi.nlm.nih.gov/pubmed/35643451 http://dx.doi.org/10.1186/s12864-022-08631-4 |
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