Cargando…

3D Printed Mini-Floating-Polypill for Parkinson’s Disease: Combination of Levodopa, Benserazide, and Pramipexole in Various Dosing for Personalized Therapy

Therapy for Parkinson’s disease is quite challenging. Numerous drugs are available for symptomatic treatment, and levodopa (LD), in combination with a dopa decarboxylase inhibitor (e.g., benserazide (BZ)), has been the drug of choice for years. As the disease progresses, therapy must be supplemented...

Descripción completa

Detalles Bibliográficos
Autores principales:	Windolf, Hellen, Chamberlain, Rebecca, Breitkreutz, Jörg, Quodbach, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145509/ https://www.ncbi.nlm.nih.gov/pubmed/35631518 http://dx.doi.org/10.3390/pharmaceutics14050931

Ejemplares similares

Precise Dosing of Pramipexole for Low-Dosed Filament Production by Hot Melt Extrusion Applying Various Feeding Methods
por: Chamberlain, Rebecca, et al.
Publicado: (2022)

Predicting Drug Release from 3D Printed Oral Medicines Based on the Surface Area to Volume Ratio of Tablet Geometry
por: Windolf, Hellen, et al.
Publicado: (2021)

Blind-Watermarking—Proof-of-Concept of a Novel Approach to Ensure Batch Traceability for 3D Printed Tablets
por: Windolf, Hellen, et al.
Publicado: (2022)

Efficacy and safety of entacapone in levodopa/carbidopa versus levodopa/benserazide treated Parkinson’s disease patients with wearing-off
por: Kuoppamäki, Mikko, et al.
Publicado: (2015)

Controlled-release levodopa methyl ester/benserazide-loaded nanoparticles ameliorate levodopa-induced dyskinesia in rats
por: Yang, Xinxin, et al.
Publicado: (2012)

Fused Deposition Modeling (FDM) 3D Printing of the Thermo-Sensitive Peptidomimetic Drug Enalapril Maleate
por: Hoffmann, Lena, et al.
Publicado: (2022)

Quality of FDM 3D Printed Medicines for Pediatrics: Considerations for Formulation Development, Filament Extrusion, Printing Process and Printer Design
por: Quodbach, Julian, et al.
Publicado: (2021)

Pharmaceutical quality of seven generic Levodopa/Benserazide products compared with original Madopar® / Prolopa®
por: Gasser, Urs E, et al.
Publicado: (2013)

Betaine protects cerebellum from oxidative stress following levodopa and benserazide administration in rats
por: Alirezaei, Masoud
Publicado: (2015)

Effects of rasagiline combined with levodopa and benserazide hydrochloride on motor function and homocysteine and IGF-1 levels in elderly patients with Parkinson’s disease
por: Yang, Yifan, et al.
Publicado: (2023)

The effect of pramipexole extended release on the levodopa equivalent daily dose in Lebanese Parkinson diseased patients
por: Faddoul, Lama, et al.
Publicado: (2018)

Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats
por: Yang, Xinxin, et al.
Publicado: (2012)

Efficacy and safety of combination therapy with pramipexole and levodopa vs levodopa monotherapy in patients with Parkinson disease: A systematic review and meta-analysis
por: Wang, Yan, et al.
Publicado: (2021)

Embedding a Sensitive Liquid-Core Waveguide UV Detector into an HPLC-UV System for Simultaneous Quantification of Differently Dosed Active Ingredients during Drug Release
por: Chamberlain, Rebecca, et al.
Publicado: (2022)

Efficacy of pramipexole combined with levodopa for Parkinson’s disease treatment and their effects on QOL and serum TNF-α levels
por: Huang, Jinzhong, et al.
Publicado: (2020)

Levodopa/Benserazide PLGA Microsphere Prevents L-Dopa–Induced Dyskinesia via Lower β-Arrestin2 in 6-Hydroxydopamine Parkinson’s Rats
por: Wang, Wen-Wen, et al.
Publicado: (2019)

Hot-Melt Extrusion of the Thermo-Sensitive Peptidomimetic Drug Enalapril Maleate
por: Hoffmann, Lena, et al.
Publicado: (2022)

Levodopa/benserazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats
por: Xie, Cheng-long, et al.
Publicado: (2014)

Electrochemical Sensor Based on Multi-Walled Carbon Nanotubes and N-Doped TiO(2) Nanoparticles for Voltametric Simultaneous Determination of Benserazide and Levodopa
por: da Silva, Elisangela Pacheco, et al.
Publicado: (2022)

Update on the use of pramipexole in the treatment of Parkinson’s disease
por: Constantinescu, Radu
Publicado: (2008)

Dyskinesias and Treatment with Pramipexole in Patients with Parkinson's Disease
por: Piedad, John C. P., et al.
Publicado: (2012)

Polypill—Friend or Foe?
por: Rishi, Rakesh Kumar
Publicado: (2011)

Benserazide-induced diarrhea – A retrospective clinical study
por: Csoti, Ilona, et al.
Publicado: (2020)

Pramipexole and its Extended Release Formulation for Parkinson’s Disease
por: Fishman, Paul S.
Publicado: (2011)

Analysis of pramipexole dose–response relationships in Parkinson’s disease
por: Wang, Ying, et al.
Publicado: (2016)

Pramipexole Inhibits Neuronal Apoptosis in Rats with Parkinson's Disease
por: Sun, Yongqi, et al.
Publicado: (2022)

The Polypill: From Promise to Pragmatism
por: Huffman, Mark D.
Publicado: (2015)

Polypill revisited – Unity in diversity
por: Dan, Gheorghe-Andrei, et al.
Publicado: (2020)

The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists
por: Deng, Huayun, et al.
Publicado: (2013)

Effect of L-DOPA/Benserazide on Propagation of Pathological α-Synuclein
por: Shimozawa, Aki, et al.
Publicado: (2019)

Beneficial effect of pramipexole for motor function and depression in Parkinson’s disease
por: Kano, Osamu, et al.
Publicado: (2008)

Retracted: Pramipexole Inhibits Neuronal Apoptosis in Rats with Parkinson's Disease
por: Healthcare Engineering, Journal of
Publicado: (2023)

Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease
por: Wan, Ying, et al.
Publicado: (2017)

Development of pH-Responsive Polypills via Semi-Solid Extrusion 3D Printing
por: Wang, Fan, et al.
Publicado: (2023)

Esophageal Atresia in a Newborn Born to a Parkinson's Mother Had L-Dopa/Benserazide Treatment during Pregnancy
por: Hamamcı, Mehmet, et al.
Publicado: (2019)

Pramipexole Extended Release: A Novel Treatment Option in Parkinson's Disease
por: Eisenreich, Wolfram, et al.
Publicado: (2010)

Reply: long-term retention rate of pramipexole in the treatment of Parkinson’s disease
por: Arbouw, Maurits E. L., et al.
Publicado: (2009)

Possible effects of pramipexole on neck muscles in a patient with Parkinson's disease
por: Filippi, Roberto, et al.
Publicado: (2014)

Customizable 3D Printed Implants Containing Triamcinolone Acetonide: Development, Analysis, Modification, and Modeling of Drug Release
por: Ponsar, Hanna, et al.
Publicado: (2023)

Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations
por: Gottschalk, Nadine, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fp2es7n53ra71urp997h1fvjen