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Dry Powder Formulation of Simvastatin Nanoparticles for Potential Application in Pulmonary Arterial Hypertension

It has been hypothesized that simvastatin could be used to treat pulmonary arterial hypertension (PAH). This study is intended to formulate a simvastatin nanoparticle dry powder inhalation (DPI) formulation. Simvastatin nanoparticles were prepared via an emulsification and homogenization-extrusion m...

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Detalles Bibliográficos
Autores principales: Zendehdel Baher, Shalaleh, Yaqoubi, Shadi, Asare-Addo, Kofi, Hamishehkar, Hamed, Nokhodchi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145523/
https://www.ncbi.nlm.nih.gov/pubmed/35631481
http://dx.doi.org/10.3390/pharmaceutics14050895