Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis

BACKGROUND: Melatonin, an indoleamine produced by the pineal gland, plays a pivotal role in maintaining circadian rhythm homeostasis. Recently, the strong antioxidant and anti-inflammatory properties of melatonin have attracted attention of researchers. We evaluated the therapeutic efficacy of melat...

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Detalles Bibliográficos
Autores principales: Huang, Jun, Li, Zhuang, Hu, Yunwei, Li, Zuoyi, Xie, Yanyan, Huang, Haixiang, Chen, Qian, Chen, Guanyu, Zhu, Wenjie, Chen, Yuxi, Su, Wenru, Chen, Xiaoqing, Liang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145533/
https://www.ncbi.nlm.nih.gov/pubmed/35624485
http://dx.doi.org/10.1186/s12974-022-02477-z

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