Cargando…

Signaling Pathway Reporter Screen with SARS-CoV-2 Proteins Identifies nsp5 as a Repressor of p53 Activity

The dysregulation of host signaling pathways plays a critical role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and viral pathogenesis. While a number of viral proteins that can block type I IFN signaling have been identified, a comprehensive analysis of SARS-CoV-2 prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Abhishek, Grams, Tristan R., Bloom, David C., Toth, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145535/
https://www.ncbi.nlm.nih.gov/pubmed/35632779
http://dx.doi.org/10.3390/v14051039