3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

Mitochondrial toxicity (Mito-Tox) risk has increased due to the administration of several classes of drugs, particularly some life-long antiretroviral drugs for HIV(+) individuals. However, no suitable in vitro assays are available to test long-term Mito-Tox (≥4 weeks). The goal of this study is to...

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Detalles Bibliográficos
Autores principales: Ding, Huifen, Jambunathan, Kalyani, Jiang, Guochun, Margolis, David M., Leng, Iris, Ihnat, Michael, Ma, Jian-Xing, Mirsalis, Jon, Zhang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145543/
https://www.ncbi.nlm.nih.gov/pubmed/35631624
http://dx.doi.org/10.3390/pharmaceutics14051042

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