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Significant Sex Differences in the Efficacy of the CSF1R Inhibitor-PLX5622 on Rat Brain Microglia Elimination

Microglia play pivotal roles in central nervous system development, homeostasis, responses to trauma, and neurodegenerative and neuropsychiatric disorders with significant sex-bias in their symptoms and prevalence. Survival of the microglia in adult brains depends on the expression of the colony-sti...

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Detalles Bibliográficos
Autores principales: Sharon, Aviv, Erez, Hadas, Spira, Micha E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145577/
https://www.ncbi.nlm.nih.gov/pubmed/35631395
http://dx.doi.org/10.3390/ph15050569