Synthesis, Biological Evaluation, and Docking Studies of Antagonistic Hydroxylated Arecaidine Esters Targeting mAChRs

The muscarinic acetylcholine receptor family is a highly sought-after target in drug and molecular imaging discovery efforts aimed at neurological disorders. Hampered by the structural similarity of the five subtypes’ orthosteric binding pockets, these efforts largely failed to deliver subtype-selec...

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Detalles Bibliográficos
Autores principales: Kilian, Jonas, Millard, Marlon, Ozenil, Marius, Krause, Dominik, Ghaderi, Khadija, Holzer, Wolfgang, Urban, Ernst, Spreitzer, Helmut, Wadsak, Wolfgang, Hacker, Marcus, Langer, Thierry, Pichler, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145622/
https://www.ncbi.nlm.nih.gov/pubmed/35630651
http://dx.doi.org/10.3390/molecules27103173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145622/
https://www.ncbi.nlm.nih.gov/pubmed/35630651
http://dx.doi.org/10.3390/molecules27103173

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