Cargando…

Correlation of Immunological and Molecular Profiles with Response to Crizotinib in Alveolar Soft Part Sarcoma: An Exploratory Study Related to the EORTC 90101 “CREATE” Trial

Alveolar soft part sarcoma (ASPS) is a rare subtype of soft tissue sarcoma characterized by an unbalanced translocation, resulting in ASPSCR1-TFE3 fusion that transcriptionally upregulates MET expression. The European Organization for Research and Treatment of Cancer (EORTC) 90101 “CREATE” phase II...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Che-Jui, Modave, Elodie, Boeckx, Bram, Kasper, Bernd, Aamdal, Steinar, Leahy, Michael G., Rutkowski, Piotr, Bauer, Sebastian, Debiec-Rychter, Maria, Sciot, Raf, Lambrechts, Diether, Wozniak, Agnieszka, Schöffski, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145625/ https://www.ncbi.nlm.nih.gov/pubmed/35628499 http://dx.doi.org/10.3390/ijms23105689

Ejemplares similares

Histopathological and Molecular Profiling of Clear Cell Sarcoma and Correlation with Response to Crizotinib: An Exploratory Study Related to EORTC 90101 “CREATE” Trial
por: Lee, Che-Jui, et al.
Publicado: (2021)

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma
por: Prenen, Hans, et al.
Publicado: (2015)

Plocabulin, a Novel Tubulin Inhibitor, Has Potent Antitumour Activity in Patient-Derived Xenograft Models of Soft Tissue Sarcoma
por: Wang, Yannick, et al.
Publicado: (2022)

A rare case of atypical/anaplastic meningioma with MDM2 amplification
por: Wylleman, Robbert, et al.
Publicado: (2018)

Therapeutic Efficacy Assessment of CK6, a Monoclonal KIT Antibody, in a Panel of Gastrointestinal Stromal Tumor Xenograft Models()()
por: Van Looy, Thomas, et al.
Publicado: (2015)

Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors
por: Wang, Yannick, et al.
Publicado: (2020)

Recurrent and novel SS18-SSX fusion transcripts in synovial sarcoma: description of three new cases
por: Przybyl, Joanna, et al.
Publicado: (2012)

Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
por: Wyn, Inez, et al.
Publicado: (2014)

Pazopanib, a Receptor Tyrosine Kinase Inhibitor, Suppresses Tumor Growth through Angiogenesis in Dedifferentiated Liposarcoma Xenograft Models()()()
por: Li, Haifu, et al.
Publicado: (2014)

Assessment of the platelet-derived growth factor receptor alpha antibody olaratumab in a panel of patient-derived soft tissue sarcoma xenografts
por: Cornillie, Jasmien, et al.
Publicado: (2019)

Characterization and assessment of the sensitivity and resistance of a newly established human gastrointestinal stromal tumour xenograft model to treatment with tyrosine kinase inhibitors
por: Van Looy, Thomas, et al.
Publicado: (2014)

Metabolomic and transcriptomic response to imatinib treatment of gastrointestinal stromal tumour in xenograft-bearing mice
por: Macioszek, Szymon, et al.
Publicado: (2023)

Frequent activation of EGFR in advanced chordomas
por: Dewaele, Barbara, et al.
Publicado: (2011)

A Sarcoma at the Site of Previous Extravasation of Adriamycin
por: Ceulemans, Joris, et al.
Publicado: (2002)

Case report: Cardiac intimal sarcoma in a young child
por: Verbeek, Sanne, et al.
Publicado: (2023)

Molecular Comparison of Imatinib-Naïve and Resistant Gastrointestinal Stromal Tumors: Differentially Expressed microRNAs and mRNAs
por: Amirnasr, Azadeh, et al.
Publicado: (2019)

Clinical implications of mutational analysis in gastrointestinal stromal tumours
por: Hoeben, A, et al.
Publicado: (2008)

Enapotamab Vedotin, an AXL-Specific Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Patient-Derived Xenograft Models of Soft Tissue Sarcoma
por: Van Renterghem, Britt, et al.
Publicado: (2022)

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours
por: Gits, C M M, et al.
Publicado: (2013)

A phase II trial with rosiglitazone in liposarcoma patients
por: Debrock, G, et al.
Publicado: (2003)

iCREATE: imaging features of primary and metastatic alveolar soft part sarcoma from the EORTC CREATE study
por: Mcaddy, Naami Charlotte, et al.
Publicado: (2020)

Enhanced Antitumor Efficacy of PhAc-ALGP-Dox, an Enzyme-Activated Doxorubicin Prodrug, in a Panel of THOP1-Expressing Patient-Derived Xenografts of Soft Tissue Sarcoma
por: Van Renterghem, Britt, et al.
Publicado: (2022)

Differences in the Tumor Molecular and Microenvironmental Landscape between Early (Non-Metastatic) and De Novo Metastatic Primary Luminal Breast Tumors
por: Lambrechts, Yentl, et al.
Publicado: (2023)

Pathogenesis of vestibular schwannoma in ring chromosome 22
por: Denayer, Ellen, et al.
Publicado: (2009)

The genetic landscape of 5T models for multiple myeloma
por: Maes, Ken, et al.
Publicado: (2018)

MDM2 Amplified Sarcomas: A Literature Review
por: Sciot, Raf
Publicado: (2021)

Molecular Heterogeneity Between Paired Primary and Metastatic Lesions from Clear Cell Renal Cell Carcinoma
por: Roussel, Eduard, et al.
Publicado: (2022)

Downstream and Intermediate Interactions of Synovial Sarcoma-Associated Fusion Oncoproteins and Their Implication for Targeted Therapy
por: Przybyl, Joanna, et al.
Publicado: (2012)

Surgical management of melanoma: an EORTC Melanoma Group survey
por: Testori, A, et al.
Publicado: (2013)

Phase II clinical trials with rhizoxin in breast cancer and melanoma. The EORTC Early Clinical Trials Group.
por: Hanauske, A. R., et al.
Publicado: (1996)

Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research
por: Lee, Che-Jui, et al.
Publicado: (2021)

Reclassification and subtyping of so-called malignant fibrous histiocytoma of bone: comparison with cytogenetic features
por: Mertens, Fredrik, et al.
Publicado: (2011)

Phase II study of rhizoxin in squamous cell head and neck cancer. The EORTC Early Clinical Trials Group.
por: Verweij, J., et al.
Publicado: (1996)

Safety and efficacy of Pazopanib in advanced soft tissue sarcoma: PALETTE (EORTC 62072) subgroup analyses
por: Cesne, Axel Le, et al.
Publicado: (2019)

CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition
por: Noeparast, Amir, et al.
Publicado: (2019)

Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups.
por: McLeod, H. L., et al.
Publicado: (1996)

Single-Centre Experience of Systemic Treatment with Vincristine, Ifosfamide, and Doxorubicin Alternating with Etoposide, Ifosfamide, and Cisplatin in Adult Patients with Ewing Sarcoma
por: Requilé, Annelies, et al.
Publicado: (2017)

Translation and validation of the EORTC brain cancer module (EORTC QLQ-BN20) for use in Iran
por: Khoshnevisan, Alireza, et al.
Publicado: (2012)

Development of an item bank for the EORTC Role Functioning Computer Adaptive Test (EORTC RF-CAT)
por: Gamper, Eva-Maria, et al.
Publicado: (2016)

Interpreting Within-Patient Changes on the EORTC QLQ-C30 and EORTC QLQ-LC13
por: Coon, Cheryl D., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5scb0vpksgjrfrhrmp21d10u57