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Design, Synthesis and Evaluation of Fused Bicyclo[2.2.2]octene as a Potential Core Scaffold for the Non-Covalent Inhibitors of SARS-CoV-2 3CL(pro) Main Protease

The emergence of SARS-CoV-2, responsible for the global COVID-19 pandemic, requires the rapid development of novel antiviral drugs that would contribute to an effective treatment alongside vaccines. Drug repurposing and development of new molecules targeting numerous viral targets have already led t...

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Detalles Bibliográficos
Autores principales:	Herlah, Barbara, Hoivik, Andrej, Jamšek, Luka, Valjavec, Katja, Yamamoto, Norio, Hoshino, Tyuji, Kranjc, Krištof, Perdih, Andrej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145702/ https://www.ncbi.nlm.nih.gov/pubmed/35631364 http://dx.doi.org/10.3390/ph15050539

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