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Activation of Nrf2/HO-1 Antioxidant Pathway by Heme Attenuates Calcification of Human Lens Epithelial Cells

Cataract, an opacification in the crystalline lens, is a leading cause of blindness. Deposition of hydroxyapatite occurs in a cataractous lens that could be the consequence of osteogenic differentiation of lens epithelial cells (LECs). Nuclear factor erythroid 2-related factor 2 (Nrf2) controls the...

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Detalles Bibliográficos
Autores principales:	Chowdhury, Arpan, Balogh, Enikő, Ababneh, Haneen, Tóth, Andrea, Jeney, Viktória
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145770/ https://www.ncbi.nlm.nih.gov/pubmed/35631320 http://dx.doi.org/10.3390/ph15050493

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