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A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus

This was an observational study based on the National Health and Nutrition Examination Survey (NHANES) and National Death Index (NDI) 2009–2014 which aimed to validate whether a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. Dietary inflammatory potential was as...

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Autores principales: Tan, Jiaxing, Liu, Nuozhou, Sun, Peiyan, Tang, Yi, Qin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145817/
https://www.ncbi.nlm.nih.gov/pubmed/35631151
http://dx.doi.org/10.3390/nu14102011
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author Tan, Jiaxing
Liu, Nuozhou
Sun, Peiyan
Tang, Yi
Qin, Wei
author_facet Tan, Jiaxing
Liu, Nuozhou
Sun, Peiyan
Tang, Yi
Qin, Wei
author_sort Tan, Jiaxing
collection PubMed
description This was an observational study based on the National Health and Nutrition Examination Survey (NHANES) and National Death Index (NDI) 2009–2014 which aimed to validate whether a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. Dietary inflammatory potential was assessed by dietary inflammatory index (DII) based on 24 h dietary recall. Mortality follow-up information was accessed from NDI, which was then merged with NHANES data following the National Center for Health Statistics (NCHS) protocols. For 15,291 participants from the general population, the average DII was 0.37 ± 1.76 and the prevalence rate of diabetes was 13.26%. DII was positively associated with fasting glucose (β = 0.83, 95% CI: 0.30, 1.36, p = 0.0022), glycohemoglobin (β = 0.02, 95% CI: 0.01, 0.03, p = 0.0009), and the risk of diabetes (OR = 1.05, 95% CI: 1.01, 1.09, p = 0.0139). For 1904 participants with diabetes and a median follow-up of 45 person-months, a total of 178 participants with diabetes died from all causes (mortality rate = 9.34%). People with diabetes who adhered to a proinflammatory diet showed a higher risk of all-cause mortality (HR = 1.71, 95%CI: 1.13, 2.58, p = 0.0108). In summary, DII was positively associated with diabetes prevalence and a proinflammatory diet may increase mortality risk in patients with diabetes mellitus.
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spelling pubmed-91458172022-05-29 A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus Tan, Jiaxing Liu, Nuozhou Sun, Peiyan Tang, Yi Qin, Wei Nutrients Article This was an observational study based on the National Health and Nutrition Examination Survey (NHANES) and National Death Index (NDI) 2009–2014 which aimed to validate whether a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. Dietary inflammatory potential was assessed by dietary inflammatory index (DII) based on 24 h dietary recall. Mortality follow-up information was accessed from NDI, which was then merged with NHANES data following the National Center for Health Statistics (NCHS) protocols. For 15,291 participants from the general population, the average DII was 0.37 ± 1.76 and the prevalence rate of diabetes was 13.26%. DII was positively associated with fasting glucose (β = 0.83, 95% CI: 0.30, 1.36, p = 0.0022), glycohemoglobin (β = 0.02, 95% CI: 0.01, 0.03, p = 0.0009), and the risk of diabetes (OR = 1.05, 95% CI: 1.01, 1.09, p = 0.0139). For 1904 participants with diabetes and a median follow-up of 45 person-months, a total of 178 participants with diabetes died from all causes (mortality rate = 9.34%). People with diabetes who adhered to a proinflammatory diet showed a higher risk of all-cause mortality (HR = 1.71, 95%CI: 1.13, 2.58, p = 0.0108). In summary, DII was positively associated with diabetes prevalence and a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. MDPI 2022-05-11 /pmc/articles/PMC9145817/ /pubmed/35631151 http://dx.doi.org/10.3390/nu14102011 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tan, Jiaxing
Liu, Nuozhou
Sun, Peiyan
Tang, Yi
Qin, Wei
A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
title A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
title_full A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
title_fullStr A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
title_full_unstemmed A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
title_short A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
title_sort proinflammatory diet may increase mortality risk in patients with diabetes mellitus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145817/
https://www.ncbi.nlm.nih.gov/pubmed/35631151
http://dx.doi.org/10.3390/nu14102011
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