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Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22

(1) Background: The systemic administration of therapeutic agents to the intestine including cytokines, such as Interleukin-22 (IL-22), is compromised by damage to the microvasculature 24 hrs after total body irradiation (TBI). At that time, there is significant death of intestinal microvascular end...

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Detalles Bibliográficos
Autores principales: Espinal, Alexis, Epperly, Michael W., Mukherjee, Amitava, Fisher, Renee, Shields, Donna, Wang, Hong, Huq, M. Saiful, Hamade, Diala Fatima, Vlad, Anda M., Coffman, Lan, Buckanovich, Ronald, Yu, Jian, Leibowitz, Brian J., van Pijkeren, Jan-Peter, Patel, Ravi B., Stolz, Donna, Watkins, Simon, Ejaz, Asim, Greenberger, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145862/
https://www.ncbi.nlm.nih.gov/pubmed/35628427
http://dx.doi.org/10.3390/ijms23105616

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