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Recent Zoonotic Spillover and Tropism Shift of a Canine Coronavirus Is Associated with Relaxed Selection and Putative Loss of Function in NTD Subdomain of Spike Protein

A canine coronavirus (CCoV) has now been reported from two independent human samples from Malaysia (respiratory, collected in 2017–2018; CCoV-HuPn-2018) and Haiti (urine, collected in 2017); these two viruses were nearly genetically identical. In an effort to identify any novel adaptations associate...

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Detalles Bibliográficos
Autores principales: Zehr, Jordan D., Pond, Sergei L. Kosakovsky, Martin, Darren P., Ceres, Kristina, Whittaker, Gary R., Millet, Jean K., Goodman, Laura B., Stanhope, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145938/
https://www.ncbi.nlm.nih.gov/pubmed/35632597
http://dx.doi.org/10.3390/v14050853