Does Glyphosate Affect the Human Microbiota?

Glyphosate is the world’s most widely used agrochemical. Its use in agriculture and gardening has been proclaimed safe because humans and other animals do not have the target enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). However, increasing numbers of studies have demonstrated risks to...

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Detalles Bibliográficos
Autores principales: Puigbò, Pere, Leino, Lyydia I., Rainio, Miia J., Saikkonen, Kari, Saloniemi, Irma, Helander, Marjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145961/
https://www.ncbi.nlm.nih.gov/pubmed/35629374
http://dx.doi.org/10.3390/life12050707
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author Puigbò, Pere
Leino, Lyydia I.
Rainio, Miia J.
Saikkonen, Kari
Saloniemi, Irma
Helander, Marjo
author_facet Puigbò, Pere
Leino, Lyydia I.
Rainio, Miia J.
Saikkonen, Kari
Saloniemi, Irma
Helander, Marjo
author_sort Puigbò, Pere
collection PubMed
description Glyphosate is the world’s most widely used agrochemical. Its use in agriculture and gardening has been proclaimed safe because humans and other animals do not have the target enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). However, increasing numbers of studies have demonstrated risks to humans and animals because the shikimate metabolic pathway is present in many microbes. Here, we assess the potential effect of glyphosate on healthy human microbiota. Our results demonstrate that more than one-half of human microbiome are intrinsically sensitive to glyphosate. However, further empirical studies are needed to determine the effect of glyphosate on healthy human microbiota.
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spelling pubmed-91459612022-05-29 Does Glyphosate Affect the Human Microbiota? Puigbò, Pere Leino, Lyydia I. Rainio, Miia J. Saikkonen, Kari Saloniemi, Irma Helander, Marjo Life (Basel) Communication Glyphosate is the world’s most widely used agrochemical. Its use in agriculture and gardening has been proclaimed safe because humans and other animals do not have the target enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). However, increasing numbers of studies have demonstrated risks to humans and animals because the shikimate metabolic pathway is present in many microbes. Here, we assess the potential effect of glyphosate on healthy human microbiota. Our results demonstrate that more than one-half of human microbiome are intrinsically sensitive to glyphosate. However, further empirical studies are needed to determine the effect of glyphosate on healthy human microbiota. MDPI 2022-05-09 /pmc/articles/PMC9145961/ /pubmed/35629374 http://dx.doi.org/10.3390/life12050707 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Puigbò, Pere
Leino, Lyydia I.
Rainio, Miia J.
Saikkonen, Kari
Saloniemi, Irma
Helander, Marjo
Does Glyphosate Affect the Human Microbiota?
title Does Glyphosate Affect the Human Microbiota?
title_full Does Glyphosate Affect the Human Microbiota?
title_fullStr Does Glyphosate Affect the Human Microbiota?
title_full_unstemmed Does Glyphosate Affect the Human Microbiota?
title_short Does Glyphosate Affect the Human Microbiota?
title_sort does glyphosate affect the human microbiota?
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145961/
https://www.ncbi.nlm.nih.gov/pubmed/35629374
http://dx.doi.org/10.3390/life12050707
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