Enhancement of Dissolving Capacity and Reducing Gastric Mucosa Irritation by Complex Formation of Resibufogenin with β-Cyclodextrin or 2-Hydroxypropyl-β-cyclodextrin

Resibufogenin (RBG) is a natural medicinal ingredient with promising cardiac protection and antitumor activity. However, poor solubility and severe gastric mucosa irritation restrict its application in the pharmaceutical field. In this study, the inclusion complex of RBG with β-cyclodextrin (β-CD) a...

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Detalles Bibliográficos
Autores principales: Liu, Nan, Chen, Huan-Ping, Yang, Zi-Meng, Xia, Ming-Yu, Wang, Dong, Zang, Ling-He, Liu, Dong-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146005/
https://www.ncbi.nlm.nih.gov/pubmed/35630687
http://dx.doi.org/10.3390/molecules27103213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146005/
https://www.ncbi.nlm.nih.gov/pubmed/35630687
http://dx.doi.org/10.3390/molecules27103213

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