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Enhancement of Dissolving Capacity and Reducing Gastric Mucosa Irritation by Complex Formation of Resibufogenin with β-Cyclodextrin or 2-Hydroxypropyl-β-cyclodextrin
Resibufogenin (RBG) is a natural medicinal ingredient with promising cardiac protection and antitumor activity. However, poor solubility and severe gastric mucosa irritation restrict its application in the pharmaceutical field. In this study, the inclusion complex of RBG with β-cyclodextrin (β-CD) a...
Autores principales: | Liu, Nan, Chen, Huan-Ping, Yang, Zi-Meng, Xia, Ming-Yu, Wang, Dong, Zang, Ling-He, Liu, Dong-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146005/ https://www.ncbi.nlm.nih.gov/pubmed/35630687 http://dx.doi.org/10.3390/molecules27103213 |
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