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Novel Oxime Synthesized from a Natural Product of Senecio nutans SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism

Senecio nutans Sch. Bip. and its constituents are reported to have antihypertensive effects. We isolated metabolite–1, a natural compound from S. nutans (4-hydroxy-3-(isopenten-2-yl)-acetophenone), and synthesized novel oxime – 1 (4-hydroxy-3-(isopenten-2-yl)-acetophenoxime) to evaluate their effect...

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Detalles Bibliográficos
Autores principales:	Palacios, Javier, Paredes, Adrián, Catalán, Marcelo A., Nwokocha, Chukwuemeka R., Cifuentes, Fredi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146311/ https://www.ncbi.nlm.nih.gov/pubmed/35630811 http://dx.doi.org/10.3390/molecules27103333

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