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Enhanced Immunogenicity of Inactivated Dengue Vaccines by Novel Polysaccharide-Based Adjuvants in Mice

Dengue fever, caused by any of four dengue viruses (DENV1-4), is a major global burden. Currently, there is no effective vaccine that prevents infection in dengue naïve populations. We tested the ability of two novel adjuvants (Advax-PEI and Advax-2), using aluminum hydroxide (alum) as control, to e...

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Detalles Bibliográficos
Autores principales:	Wu, Shuenn-Jue, Ewing, Dan, Sundaram, Appavu K., Chen, Hua-Wei, Liang, Zhaodong, Cheng, Ying, Jani, Vihasi, Sun, Peifang, Gromowski, Gregory D., De La Barrera, Rafael A., Schilling, Megan A., Petrovsky, Nikolai, Porter, Kevin R., Williams, Maya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146336/ https://www.ncbi.nlm.nih.gov/pubmed/35630476 http://dx.doi.org/10.3390/microorganisms10051034

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