N,N-Diethyl-3-toluamide Formulation Based on Ethanol Containing 0.1% 2-Hydroxypropyl-β-cyclodextrin Attenuates the Drug’s Skin Penetration and Prolongs the Repellent Effect without Stickiness

N,N-diethyl-3-toluamide (DEET) is one of the most widely used insect repellents in the world. It was reported that a solution containing 6–30% cyclodextrin (CD) as a solvent instead of ethanol (EtOH) provided an enhancement of the repellent action time duration of the DEET formulation, although the...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Kawaguchi, Mayu, Minami, Misa, Matsumoto, Kana, Sasabe, Tatsuji, Nobuhara, Kenji, Matsubara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146378/
https://www.ncbi.nlm.nih.gov/pubmed/35630650
http://dx.doi.org/10.3390/molecules27103174

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