Cargando…
Structural Features of Clostridium botulinum Neurotoxin Subtype A2 Cell Binding Domain
Botulinum neurotoxins (BoNT) are a group of clostridial toxins that cause the potentially fatal neuroparalytic disease botulism. Although highly toxic, BoNTs are utilized as therapeutics to treat a range of neuromuscular conditions. Several serotypes (BoNT/A-/G, /X) have been identified with vastly...
Autores principales: | Gregory, Kyle S., Mahadeva, Tejaswini B., Liu, Sai Man, Acharya, K. Ravi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146395/ https://www.ncbi.nlm.nih.gov/pubmed/35622602 http://dx.doi.org/10.3390/toxins14050356 |
Ejemplares similares
-
A Comprehensive Structural Analysis of Clostridium botulinum Neurotoxin A Cell-Binding Domain from Different Subtypes
por: Gregory, Kyle S., et al.
Publicado: (2023) -
Crystal Structures of Botulinum Neurotoxin Subtypes A4 and A5 Cell Binding Domains in Complex with Receptor Ganglioside
por: Gregory, Kyle S., et al.
Publicado: (2022) -
Crystal structure of botulinum neurotoxin subtype A3 cell binding domain in complex with GD1a co‐receptor ganglioside
por: Gregory, Kyle S., et al.
Publicado: (2020) -
High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA
por: Davies, Jonathan R., et al.
Publicado: (2018) -
Crystal Structures of the Clostridium botulinum Neurotoxin A6 Cell Binding Domain Alone and in Complex with GD1a Reveal Significant Conformational Flexibility
por: Gregory, Kyle S., et al.
Publicado: (2022)